VTA1 and CHMP1B

Data Source:
BioGRID (two hybrid)

		VTA1	CHMP1B
Description		vesicle trafficking 1	charged multivesicular body protein 1B
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GO Annotations	Cellular Component	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	ESCRT III Complex Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Membrane Coat Midbody Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding	Protein Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly	Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Cell Division Midbody Abscission Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863)	Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2	19 interacting genes: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN MITD1 PICK1 RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B VTA1
Entrez ID		51534	57132
HPRD ID		09855	12106
Ensembl ID		ENSG00000009844	ENSG00000255112
Uniprot IDs		A0A087WY55 Q9NP79	Q7LBR1
PDB IDs		2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E	3EAB 3JC1 4TXQ 4TXR 6E8G 6TZ4 6TZ5 6TZ9
Enriched GO Terms of Interacting Partners?
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