DYNLT1 and ERO1A

Data Source:
BioGRID (affinity chromatography technology)

		DYNLT1	ERO1A
Description		dynein light chain Tctex-type 1	endoplasmic reticulum oxidoreductase 1 alpha
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GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Protein Phosphopantetheinylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Neutrophil degranulation	Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	12 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 LHX4 LINC01554 P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		6993	30001
HPRD ID		15987	13278
Ensembl ID		ENSG00000146425	ENSG00000197930
Uniprot IDs		P63172	Q96HE7
PDB IDs		5JPW	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
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