ERO1A and GPX7

Data Source:
BioGRID (protein complementation assay)

		ERO1A	GPX7
Description		endoplasmic reticulum oxidoreductase 1 alpha	glutathione peroxidase 7
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding
	Biological Process	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Protein Phosphopantetheinylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification
Pathways		Insulin processing Detoxification of Reactive Oxygen Species	Detoxification of Reactive Oxygen Species
Drugs			Glutathione Glutathione Glutathione disulfide
Diseases
GWAS		Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)	Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		12 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 LHX4 LINC01554 P4HB PDIA3 PDILT PELI2 RHOU	13 interacting genes: ASPH CEP70 CPEB2 CPNE7 ERO1A GET3 NCALD NTAQ1 SGTA SGTB TCF25 UBQLN2 UBQLN4
Entrez ID		30001	2882
HPRD ID		13278	13606
Ensembl ID		ENSG00000197930	ENSG00000116157
Uniprot IDs		Q96HE7	Q96SL4
PDB IDs		3AHQ 3AHR	2P31
Enriched GO Terms of Interacting Partners?
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