PPP1R11 and UBXN2B

Data Source:
BioGRID (pull down)

		PPP1R11	UBXN2B
Description		protein phosphatase 1 regulatory inhibitor subunit 11	UBX domain protein 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Spindle Pole Centrosome
	Molecular Function	Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Phosphoprotein Phosphatase Activity Defense Response To Gram-positive Bacterium	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lipid metabolism phenotypes ( 22286219)	Gallstone disease ( 27094239) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Loneliness ( 27629369) Low density lipoprotein cholesterol levels ( 29403010) Medication use (HMG CoA reductase inhibitors) ( 31015401) Narcolepsy with cataplexy ( 23496005) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Total cholesterol levels ( 29403010) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		8 interacting genes: IFT20 LATS1 PPP1CA PPP1CB PPP1CC UBXN2B VCP YAF2	14 interacting genes: CRX FAM104A INCA1 MEOX1 MEOX2 NGLY1 PAX5 PAX6 PIN1 PPP1R11 UBXN6 VAT1L VCP XAF1
Entrez ID		6992	137886
HPRD ID		09449	18973
Ensembl ID		ENSG00000204619	ENSG00000215114
Uniprot IDs		A2BEK1 O60927	E5RJ36 Q14CS0
PDB IDs
Enriched GO Terms of Interacting Partners?
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