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BUB1 and TSTD2
Data Source:
BioGRID
(two hybrid)
BUB1
TSTD2
Description
BUB1 mitotic checkpoint serine/threonine kinase
thiosulfate sulfurtransferase like domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Nuclear Chromosome Outer Kinetochore
Nucleoplasm
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Cellular_component
Molecular Function
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Molecular_function
Protein Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Regulation Of Sister Chromatid Cohesion
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Population Proliferation
Viral Process
Cell Division
Meiotic Sister Chromatid Cohesion, Centromeric
Regulation Of Chromosome Segregation
Biological_process
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes
63 interacting genes:
AKT1
ALDOB
ANP32B
AOPEP
AP1B1
AP2B1
AP3B1
AP4B1
APC
ARIH2
BAAT
BUB3
CCDC180
CDC14B
CDC20
CDK1
CDK8
CORO2A
CRK
CTSV
CYLC2
DVL1
EIF4EBP1
FANCC
FBP1
FBP2
FBXO7
FRAT2
GALNT12
HDAC1
HEMGN
HRAS
HSD17B3
IGFBP3
KNL1
LEF1
MAP2K1
MAPK3
MSANTD3
NANS
PLK1
PPP2CB
PPP3R2
RAE1
RASA1
RDH12
SEC61B
SFRP2
SFRP4
SHC1
SMAD1
STX17
SVIL
TBC1D2
TDRD7
TGFB1
TMEFF1
TMOD1
TRMO
TSTD2
XPA
ZNF189
ZNF510
33 interacting genes:
AGR2
APC
AURKA
BLZF1
BUB1
CCND1
DCC
EGFR
FLCN
IKZF1
IKZF3
INCA1
ISY1-RAB43
L3MBTL3
LHX4
MCC
MEOX2
MLH3
MUTYH
ODC1
PICK1
PTPRJ
REL
SMAD4
SSX2IP
TCF4
TOX3
VPS52
ZBTB14
ZFPL1
ZNF438
ZNF774
ZRANB1
Entrez ID
699
158427
HPRD ID
03907
16679
Ensembl ID
ENSG00000169679
ENSG00000136925
Uniprot IDs
B4DYG2
O43683
Q5T7W7
PDB IDs
2LAH
4A1G
4QPM
4R8Q
5DMZ
6F7B
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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