TSTD2 and MUTYH

Data Source:
BioGRID (two hybrid)

		TSTD2	MUTYH
Description		thiosulfate sulfurtransferase like domain containing 2	mutY DNA glycosylase
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Molecular_function Protein Binding	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Biological_process	DNA Repair Base-excision Repair Mismatch Repair Depurination
Pathways
Drugs
Diseases			Familial adenomatous polyposis
GWAS			Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		33 interacting genes: AGR2 APC AURKA BLZF1 BUB1 CCND1 DCC EGFR FLCN IKZF1 IKZF3 INCA1 ISY1-RAB43 L3MBTL3 LHX4 MCC MEOX2 MLH3 MUTYH ODC1 PICK1 PTPRJ REL SMAD4 SSX2IP TCF4 TOX3 VPS52 ZBTB14 ZFPL1 ZNF438 ZNF774 ZRANB1	19 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TSTD2 XPA
Entrez ID		158427	4595
HPRD ID		16679	05380
Ensembl ID		ENSG00000136925	ENSG00000132781
Uniprot IDs		Q5T7W7	D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7
PDB IDs			1X51 3N5N
Enriched GO Terms of Interacting Partners?
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