TRA and EDEM3

Data Source:
BioGRID (pull down)

		TRA	EDEM3
Description		T cell receptor alpha locus	ER degradation enhancing alpha-mannosidase like protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Alpha-beta T Cell Receptor Complex	Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Signaling Receptor Activity	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding
	Biological Process	Detection Of Tumor Cell T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target	Carbohydrate Metabolic Process Protein Glycosylation Response To Unfolded Protein Mannose Trimming Involved In Glycoprotein ERAD Pathway
Pathways			ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Narcolepsy ( 24204295) Periodontal disease-related phenotype (Socransky) ( 26962152)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		15 interacting genes: CANX CD247 CD3D CD3G EDEM3 HLA-A HLA-B HLA-DRB1 HSPA5 LEF1 NCOA6 SNTA1 TRAT1 TRB TRD	2 interacting genes: TRA TXNDC5
Entrez ID		6955	80267
HPRD ID		01736	10724
Ensembl ID			ENSG00000116406
Uniprot IDs			Q9BZQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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