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TCF3 and TCAF1
Data Source:
BioGRID
(two hybrid, two hybrid)
TCF3
TCAF1
Description
transcription factor 3
TRPM8 channel associated factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Plasma Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Protein Heterodimerization Activity
Repressing Transcription Factor Binding
Vitamin D Response Element Binding
E-box Binding
Protein Binding
Ion Channel Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
B Cell Lineage Commitment
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
B Cell Differentiation
Immunoglobulin V(D)J Recombination
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Muscle Cell Differentiation
Regulation Of Hematopoietic Stem Cell Differentiation
Regulation Of Anion Channel Activity
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Targeting To Membrane
Positive Regulation Of Anion Channel Activity
Pathways
Myogenesis
Myogenesis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
GWAS
Hodgkin's lymphoma (
29196614
24920014
)
Objective response to lithium treatment (
26503763
)
Interacting Genes
67 interacting genes:
AEBP1
ASCL3
AURKA
BHLHA15
BHLHE40
CALM1
CALM3
CBFA2T3
CREBBP
CTNNB1
DACH1
DAXX
ELK3
EP300
FERD3L
GLIS1
HAND1
HAND2
HOXA1
ID1
ID2
ID3
KAT2A
KAT2B
LMX1A
LMX1B
LYL1
MAPK1
MAPK3
MAPKAPK2
MAPKAPK3
MDFI
MEN1
MSC
MYF5
MYF6
MYOD1
MYOG
NEDD9
NEUROD1
NHLH1
NSD3
PARP1
PDX1
PSMD4
PSMD9
RALGAPA1
RPL37
RUNX1T1
SCX
SKP2
SRF
SUPT3H
TADA2A
TAL1
TAL2
TCAF1
TCF12
TCF21
TCF4
TFPT
TLE1
TRRAP
TWIST1
TWIST2
UBE2I
USF1
37 interacting genes:
BIRC2
CAMK2A
CEP70
CNKSR1
COIL
CYSRT1
DISC1
EFEMP2
IKZF3
IKZF4
KRTAP1-3
KRTAP10-8
KRTAP13-2
KRTAP6-3
MAD1L1
MID2
NBPF19
NFYA
NOTCH2NLA
PRDM14
PRDM6
RBAK
SCYL3
SF3B4
SPRY2
TAX1BP1
TCF3
TFIP11
TRAF2
TRIM42
TRIM54
TRIP6
UBC
ZNF143
ZNF24
ZNF263
ZNF592
Entrez ID
6929
9747
HPRD ID
00918
13813
Ensembl ID
ENSG00000071564
ENSG00000198420
Uniprot IDs
A0A0A0MRB7
P15923
X6REB3
B4DST7
Q9Y4C2
PDB IDs
1HLH
2MH0
2YPA
2YPB
3U5V
6MGN
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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