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TAZ and LATS2
Data Source:
BioGRID
(enzymatic study)
TAZ
LATS2
Description
tafazzin
large tumor suppressor kinase 2
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Spindle Pole
Nucleus
Cytosol
Centriolar Satellite
Molecular Function
1-acylglycerol-3-phosphate O-acyltransferase Activity
O-acyltransferase Activity
1-acylglycerophosphocholine O-acyltransferase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Muscle Contraction
Inner Mitochondrial Membrane Organization
Heart Development
Skeletal Muscle Tissue Development
Hemopoiesis
Cardiolipin Biosynthetic Process
Mitochondrial Respiratory Chain Complex I Assembly
Cardiolipin Acyl-chain Remodeling
Cristae Formation
Mitochondrial ATP Synthesis Coupled Electron Transport
Cardiac Muscle Tissue Development
Cardiac Muscle Contraction
G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Hormone-mediated Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Peptidyl-serine Phosphorylation
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Organ Growth
Cell Division
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Mitochondrial protein import
Mitochondrial protein import
Acyl chain remodeling of CL
Signaling by Hippo
Drugs
Diseases
3-Methylglutaconic aciduria (MGCA)
Barth syndrome (BTHS)
Dilated cardiomyopathy (DCM)
GWAS
3-month functional outcome in ischaemic stroke (modified Rankin score) (
30796134
)
Refractive error (
32231278
)
Interacting Genes
9 interacting genes:
BTRC
CHGB
CSNK1E
GSK3B
LATS1
LATS2
RUNX1
SLC9A3R2
YWHAE
67 interacting genes:
ABL1
AJUBA
AKT1
ARAF
ARNT
AURKA
AURKB
BECN1
BRAF
CBLC
CCND2
CCNE1
CD44
CDK2
CDK4
CDK6
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CHEK1
CHEK2
CTNNB1
DYRK1A
EPHA2
ERBB2
EZH2
FGFR4
FHL3
FZR1
GLIS1
GLIS2
GRAP2
GRM1
HGF
HIF1A
KAT2A
KDELR2
KIF23
MAP2K3
MAP2K5
MAPK14
MDM4
MET
MOB3A
MOB3B
MOB3C
MOB4
MYC
NF2
NFIC
PDGFRA
RAF1
RASSF1
RELA
SMAD2
SNAI1
STK11
STK3
SUZ12
TAZ
TEAD2
TP53
TSC1
WWTR1
YWHAG
YWHAZ
Entrez ID
6901
26524
HPRD ID
02316
07277
Ensembl ID
ENSG00000102125
ENSG00000150457
Uniprot IDs
A0A0S2Z4E6
A0A0S2Z4F4
A0A0S2Z4K0
A0A0S2Z4K9
A0A494C0C5
A0A499FJ53
A6XNE1
Q16635
A0A024RDM3
Q9NRM7
PDB IDs
4ZRI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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