TAF7 and TAF2

Data Source:
HPRD (in vivo, in vitro)

		TAF7	TAF2
Description		TATA-box binding protein associated factor 7	TATA-box binding protein associated factor 2
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GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding TFIIH-class Transcription Factor Complex Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Negative Regulation Of Histone H4 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	G2/M Transition Of Mitotic Cell Cycle Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278)	Heart rate response to exercise ( 29769521)
Interacting Genes		27 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	14 interacting genes: ESR1 H3-4 PUF60 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9
Entrez ID		6879	6873
HPRD ID		07196	07060
Ensembl ID		ENSG00000178913	ENSG00000064313
Uniprot IDs		Q15545	A0A024R9E6 B3KMD8 Q6P1X5
PDB IDs		4RGW 5FUR 6MZL 6MZM	5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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