ST14 and RGS16

Data Source:
BioGRID (two hybrid)

		ST14	RGS16
Description		ST14 transmembrane serine protease matriptase	regulator of G protein signaling 16
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane	Cytoplasm Plasma Membrane Intrinsic Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching Cornification	G Protein-coupled Receptor Signaling Pathway Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Formation of the cornified envelope Formation of the cornified envelope	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs		Urokinase Benzamidine Camostat
Diseases		Ichthyosis with hypotrichosis
GWAS		Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)	Chronotype ( 26955885 30696823 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416)
Interacting Genes		17 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1	14 interacting genes: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14
Entrez ID		6768	6004
HPRD ID		06005	03945
Ensembl ID		ENSG00000149418	ENSG00000143333
Uniprot IDs		Q9Y5Y6	O15492
PDB IDs		1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T	2BT2 2IK8
Enriched GO Terms of Interacting Partners?
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