ST14 and CDCP1

Data Source:
HPRD (in vivo)

		ST14	CDCP1
Description		ST14 transmembrane serine protease matriptase	CUB domain containing protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane	Extracellular Region Plasma Membrane Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Protein Binding
	Biological Process	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching Cornification
Pathways		Formation of the cornified envelope Formation of the cornified envelope
Drugs		Urokinase Benzamidine Camostat
Diseases		Ichthyosis with hypotrichosis
GWAS		Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)	Acne (severe) ( 24927181) Blood protein levels ( 30072576) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Macular thickness ( 30535121) Metabolite levels ( 23823483) Statin-induced myopathy (severe) ( 31220337)
Interacting Genes		17 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1	6 interacting genes: CLK1 PLG PRKCD SDCBP SRC ST14
Entrez ID		6768	64866
HPRD ID		06005	16696
Ensembl ID		ENSG00000149418	ENSG00000163814
Uniprot IDs		Q9Y5Y6	Q9H5V8
PDB IDs		1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T
Enriched GO Terms of Interacting Partners?
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