RGS16 and ST14

Data Source:
BioGRID (two hybrid)

		RGS16	ST14
Description		regulator of G protein signaling 16	ST14 transmembrane serine protease matriptase
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Intrinsic Component Of Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching Cornification
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	Formation of the cornified envelope Formation of the cornified envelope
Drugs			Urokinase Benzamidine Camostat
Diseases			Ichthyosis with hypotrichosis
GWAS		Chronotype ( 26955885 30696823 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416)	Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		14 interacting genes: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14	17 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1
Entrez ID		6004	6768
HPRD ID		03945	06005
Ensembl ID		ENSG00000143333	ENSG00000149418
Uniprot IDs		O15492	Q9Y5Y6
PDB IDs		2BT2 2IK8	1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T
Enriched GO Terms of Interacting Partners?
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