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SSX2 and RNF2
Data Source:
BioGRID
(pull down)
SSX2
RNF2
Description
SSX family member 2
ring finger protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Molecular Function
Protein Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
RING-like Zinc Finger Domain Binding
Biological Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Germ Cell Development
Anterior/posterior Axis Specification
Gene Expression
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Drugs
Diseases
Synovial sarcoma
GWAS
Clopidogrel active metabolite levels (
28207573
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Obesity-related traits (
23251661
)
Interacting Genes
17 interacting genes:
AKAP9
BLZF1
FLACC1
FTSJ3
KRT40
LRRC45
MAGEC2
PHLDA2
RAB3IP
RNF2
SSX2IP
SYCE1
TAX1BP1
TNPO3
TRAPPC2L
ZBED1
ZMIZ2
59 interacting genes:
ABCB1
AMBRA1
AUTS2
BAALC
BMI1
CASP3
CASP9
CBX2
CBX4
DYSF
ERG
H2AC18
H2AC20
H2AC4
H3-4
KAT8
KMT2A
MBD1
MTNR1A
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF6
PGP
PHB2
PHC1
PHC2
PLK1
PSMC4
RING1
RRM1
RYBP
SIK1
SMURF2
SSX2
TARDBP
TFCP2
TSC22D2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
USP11
USP19
WASHC1
YAF2
Entrez ID
6757
6045
HPRD ID
02180
07028
Ensembl ID
ENSG00000241476
ENSG00000121481
Uniprot IDs
Q16385
R9QTR3
Q99496
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
4R8P
4S3O
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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