SST and SSTR5

Data Source:
HPRD (in vivo)

		SST	SSTR5
Description		somatostatin	somatostatin receptor 5
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Neuronal Cell Body Synapse	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Heat Response To Acidic PH Regulation Of Cell Migration Response To Drug Response To Amino Acid Response To Steroid Hormone	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Vapreotide Pasireotide Lanreotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)	Logical memory (immediate recall) in normal cognition ( 29274321) Polycystic ovary syndrome ( 25574032)
Interacting Genes		6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	9 interacting genes: ADCY10 CNR1 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1
Entrez ID		6750	6755
HPRD ID		08920	01677
Ensembl ID		ENSG00000157005	ENSG00000162009
Uniprot IDs		P61278	P35346
PDB IDs		1P2W 2MI1
Enriched GO Terms of Interacting Partners?
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