SST and SSTR1

Data Source:
HPRD (in vivo)

		SST	SSTR1
Description		somatostatin	somatostatin receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Neuronal Cell Body Synapse	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Heat Response To Acidic PH Regulation Of Cell Migration Response To Drug Response To Amino Acid Response To Steroid Hormone	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Glutamate Receptor Signaling Pathway Neuropeptide Signaling Pathway Spermatogenesis Negative Regulation Of Cell Population Proliferation Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Estradiol Stimulus Cellular Response To Leukemia Inhibitory Factor
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Pasireotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)	Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Interacting Genes		6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	5 interacting genes: CORT PRMT5 SNTA1 SST SSTR5
Entrez ID		6750	6751
HPRD ID		08920	01673
Ensembl ID		ENSG00000157005	ENSG00000139874
Uniprot IDs		P61278	P30872 Q86SW9
PDB IDs		1P2W 2MI1
Enriched GO Terms of Interacting Partners?
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