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SPN and CTSA
Data Source:
BioGRID
(two hybrid)
SPN
CTSA
Description
sialophorin
cathepsin A
Image
No pdb structure
GO Annotations
Cellular Component
Uropod
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Microvillus
External Side Of Plasma Membrane
Cell Surface
Membrane
PML Body
Extracellular Exosome
Extracellular Region
Lysosome
Endoplasmic Reticulum
Membrane
Azurophil Granule Lumen
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Lumenal Side Of Lysosomal Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Hsp70 Protein Binding
Heat Shock Protein Binding
Carboxypeptidase Activity
Serine-type Carboxypeptidase Activity
Enzyme Activator Activity
Biological Process
T-helper 1 Cell Lineage Commitment
Chemotaxis
Immune Response
Cellular Defense Response
Negative Regulation Of Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Signal Transduction
Cell Surface Receptor Signaling Pathway
Interferon-gamma Production
Positive Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Regulation Of Immune Response
Leukocyte Migration
Leukocyte Tethering Or Rolling
Regulation Of T Cell Migration
Positive Regulation Of T Cell Migration
Proteolysis
Glycosphingolipid Metabolic Process
Intracellular Protein Transport
Regulation Of Protein Stability
Neutrophil Degranulation
Regulation Of Catalytic Activity
Regulation Of Chaperone-mediated Autophagy
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
Cell surface interactions at the vascular wall
Basigin interactions
Glycosphingolipid metabolism
MHC class II antigen presentation
Sialic acid metabolism
Defective NEU1 causes sialidosis
Neutrophil degranulation
Drugs
Diseases
Galactosialidosis
GWAS
Interacting Genes
18 interacting genes:
ARL13B
CLCA4
CTNNB1
CTSA
CXCL16
CYBC1
DAXX
ERGIC3
EZR
FYN
ICAM1
LGALS1
LMNA
MSN
PLP2
SGTA
SIGLEC1
UBQLN2
45 interacting genes:
AHNAK2
AQP2
AQP6
ARL13B
ASPH
BSND
CD79A
COQ9
CPLX4
CREB3L1
CSPG5
ERGIC3
FAM209A
FKBP7
FNDC9
GLB1
GORAB
HIBADH
LAMP2
LMNA
LTB4R2
MFSD14B
MGST3
MUC1
MYG1
NEU1
PSCA
REEP4
RHBDD1
RNF122
SAR1A
SGMS2
SIGLEC12
SLC18A1
SLC30A2
SPN
SSMEM1
STX2
THAP4
TMEM139
TMEM154
TMEM237
TMEM31
TMEM35A
TMX2
Entrez ID
6693
5476
HPRD ID
06770
02020
Ensembl ID
ENSG00000197471
ENSG00000064601
Uniprot IDs
A0A024R629
P16150
B4E324
P10619
X6R5C5
X6R8A1
PDB IDs
1IVY
3BP4
3BP7
3BXN
4AZ0
4AZ3
4CI9
4CIA
4CIB
4MWS
4MWT
6WIA
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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