EXOC1 and CCDC88A

Data Source:
BioGRID (two hybrid)

		EXOC1	CCDC88A
Description		exocyst complex component 1	coiled-coil domain containing 88A
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Centriole Cytosol Plasma Membrane Membrane Lamellipodium COPI-coated Golgi To ER Transport Vesicle Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding	G-protein Alpha-subunit Binding Actin Binding Protein Kinase C Binding Guanyl-nucleotide Exchange Factor Activity GDP-dissociation Inhibitor Activity Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Microtubule Binding G-protein Gamma-subunit Binding Phosphatidylinositol Binding SH2 Domain Binding Protein Homodimerization Activity Vascular Endothelial Growth Factor Receptor 2 Binding Protein Kinase B Binding Dynein Light Intermediate Chain Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus	Regulation Of Protein Phosphorylation DNA Replication Regulation Of DNA Replication Small GTPase Mediated Signal Transduction Nervous System Development Regulation Of Neuron Projection Development Cell Migration Lamellipodium Assembly Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization TOR Signaling Activation Of Protein Kinase Activity Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Cell Population Proliferation Positive Regulation Of Cilium Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Membrane Organization Maintenance Of Protein Location In Plasma Membrane Positive Regulation Of Protein Localization To Cilium
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Height ( 21998595) Periventricular white matter hyperintensities ( 32517579) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	11 interacting genes: AKT1 BRAF DISC1 EGFR EXOC1 GNAI3 INSR KDR NDEL1 PRKACA PTPN6
Entrez ID		55763	55704
HPRD ID		07615	11131
Ensembl ID		ENSG00000090989	ENSG00000115355
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	A0A2U3TZV9 O14997 Q3V6T2
PDB IDs			6MHF
Enriched GO Terms of Interacting Partners?
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