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SOX10 and EXOC5
Data Source:
BioGRID
(two hybrid)
SOX10
EXOC5
Description
SRY-box transcription factor 10
exocyst complex component 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Extrinsic Component Of Mitochondrial Outer Membrane
Exocyst
Cytoplasm
Cytosol
Midbody
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Identical Protein Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Protein Binding
Small GTPase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Neural Crest Cell Migration
Morphogenesis Of An Epithelium
Positive Regulation Of Neuroblast Proliferation
Regulation Of Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Peripheral Nervous System Development
Anatomical Structure Morphogenesis
Negative Regulation Of Schwann Cell Proliferation
Oligodendrocyte Development
Positive Regulation Of Gliogenesis
Central Nervous System Myelination
Melanocyte Differentiation
Positive Regulation Of Myelination
Lacrimal Gland Development
Cellular Response To Drug
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Enteric Nervous System Development
Digestive Tract Morphogenesis
Developmental Growth
Oligodendrocyte Differentiation
Morphogenesis Of A Branching Epithelium
Cellular Response To Progesterone Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Exocytosis
Post-Golgi Vesicle-mediated Transport
Golgi To Plasma Membrane Transport
Protein Transport
Pathways
EGR2 and SOX10-mediated initiation of Schwann cell myelination
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Insulin processing
VxPx cargo-targeting to cilium
Drugs
Diseases
46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
Waardenburg syndrome (WS)
GWAS
Mean spheric corpuscular volume (
32888494
)
Alcohol consumption (
23743675
)
Chronotype (
30696823
)
Response to ranibizumab in age-related macular degeneration (exudative) (
30054556
)
Interacting Genes
35 interacting genes:
ALX4
C10orf55
CDK6
CEBPA
CRX
DAZAP2
DLX5
EGR2
EXOC5
GSK3B
HHEX
HIVEP1
HOXA3
HOXC4
HSF4
JUN
MAGED1
MEOX1
NMI
OLIG2
PAX3
PAX6
POU3F2
POU3F3
POU5F1
POU6F2
PRRX1
PRRX2
SP1
SUMO1
SUMO2
SUMO3
TCF12
UBE2I
UTF1
43 interacting genes:
ACTR3B
ADCK1
ARF6
BARD1
BRMS1L
C1orf216
CCDC102B
CDH2
CRYBB1
DEUP1
DNAAF4
EDRF1
ENO2
EXOC6
EXOC6B
FGA
FRMD6
HDDC3
HGS
ICA1
IFT57
KIFC3
KXD1
MAGEA3
MAGEA6
OAS1
PRKCG
PSTPIP1
PTK6
PYCARD
RAB14
RAB4A
RAB4B
RALA
SOX10
SPACA9
TBX21
THOC1
TNPO2
TTC23L
TXLNB
TXNL4A
USP2
Entrez ID
6663
10640
HPRD ID
03752
07258
Ensembl ID
ENSG00000100146
ENSG00000070367
Uniprot IDs
A0A024R1N6
P56693
O00471
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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