SNRPC and HOXA1

Data Source:
BioGRID (two hybrid)

		SNRPC	HOXA1
Description		small nuclear ribonucleoprotein polypeptide C	homeobox A1
Image			No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Chromatin Nucleus
	Molecular Function	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Pre-mRNA 5'-splice Site Binding Protein Homodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis
Pathways		mRNA Splicing - Major Pathway	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases			Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol ( 25961943) Low density lipoprotein cholesterol levels ( 32154731) Obese vs. thin ( 30677029) Refractive error ( 32231278) Systemic lupus erythematosus ( 24871463)	Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)
Interacting Genes		82 interacting genes: AGGF1 AKAP8L ANKRD10 ARHGAP9 BAG4 BCAS2 BOLL C19orf54 CREM CYSRT1 DAZAP2 DDX42 ECM1 EWSR1 EXOSC8 EYA2 FAM168A FAM168B FHL3 FUBP1 GIGYF1 GOLGA2 HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH2 HNRNPUL1 HOXA1 HSD17B14 ILF3 INTS11 JMJD7 KHDRBS3 KLF1 KRTAP11-1 KRTAP13-2 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP22-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 MAGED1 METTL27 MGAT5B MKRN3 NCAPH2 NCKIPSD ODAM PLA2G10 PRDM14 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RAMAC RBFOX2 RBM11 RBM4 RBPMS RERE RFX6 RNF31 RUNX1 SEC23B SNRNP70 SPAG8 SS18L1 STH TENT5A TLE5 TRIB3 UFSP1 WDR77 WWOX WWP2	292 interacting genes: ADAM12 ADAMTSL4 AGXT ALG13 ALPP AMMECR1 AMOT ANKS1A ARID5A ARMC7 ATG9B ATP23 BAG4 BAHD1 BATF2 BHLHB9 BLCAP BLZF1 BSCL2 BUD31 C11orf1 C11orf16 CATSPER1 CCDC120 CCDC33 CCN3 CCN4 CCN5 CCNK CD164 CDPF1 CERCAM CFP CHIC2 CHRD CHRDL2 CNFN CNNM3 COL8A1 CREB5 CUTA CXCL16 CYHR1 CYP21A2 CYSRT1 DOCK2 DOCK3 DOK3 DTX2 DUSP10 DUSP22 EFEMP1 EFEMP2 EGFL7 ENKD1 EPDR1 ESM1 ESR2 EVA1B FAAP100 FAM219B FAM221A FBLN1 FHL3 FHL5 FOXH1 FOXN1 FRS3 FST FUCA2 GAS8 GATA1 GCM2 GDF15 GNE GP9 GPS2 GRN GSTP1 GUCD1 HEXB HEXIM2 HEY2 HOXB9 HR HSD3B7 ID3 IGFL1 IGFN1 INCA1 INO80B IRX6 ITGB4 KCTD9 KDM1A KPRP KRT31 KRT33B KRT34 KRT35 KRT37 KRT38 KRT40 KRT81 KRT82 KRT83 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP23-1 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2B LCE2C LCE2D LCE3C LCE3E LCE4A LCE5A LGALS13 LGALS4 LMX1B LNX1 LONRF1 LPXN MACO1 MAPKBP1 MDFI MFAP2 MGAT5B MKRN3 MYO15B MYPOP N4BP2L2 NBPF19 NCK2 NECTIN2 NEDD9 NEK6 NELL2 NFKBID NOTCH2NLA NR1D2 NTN4 NXF1 ODF1 OIT3 P2RY6 PAX6 PBX2 PCSK5 PCYOX1 PHETA1 PIK3R1 PIN1 PITX1 PITX2 PKNOX1 PLEKHN1 PLLP PLSCR1 PLSCR2 PLSCR3 PLSCR4 PPP1R32 PRICKLE4 PRMT6 PROP1 PSMB1 PTH1R PVR QARS1 RALGDS RANBP3 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS19 RGS20 RNF208 RSPO2 RTN4R SCT SDCBP SIVA1 SLC15A3 SLC23A1 SLIT1 SLPI SNRPB SNRPC SPATA12 SPATA18 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D SSUH2 STX11 SUV39H1 TBC1D10C TBX15 TCF19 TCF3 TEKT4 TEKT5 TGFB1 TGM7 THAP7 TLE5 TNS2 TRAF1 TRAF2 TRAF4 TRAPPC6A TRIM42 TRIM55 TRIM63 TRIM8 TRIP6 TSPAN4 UBL5 UNKL VASN VWC2 VWC2L WDR83 WWOX YIPF3 YPEL3 ZBTB16 ZIM2 ZMAT1 ZNF417 ZNF587 ZNF688 ZNF774 ZNF837 ZNF843
Entrez ID		6631	3198
HPRD ID		04630	00843
Ensembl ID		ENSG00000124562	ENSG00000105991
Uniprot IDs		P09234 Q5TAL4	P49639
PDB IDs		2VRD 3CW1 4PJO 6ELD 6QX9
Enriched GO Terms of Interacting Partners?
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