SNRPA and NDUFAF3

Data Source:
BioGRID (two hybrid, two hybrid)

		SNRPA	NDUFAF3
Description		small nuclear ribonucleoprotein polypeptide A	NADH:ubiquinone oxidoreductase complex assembly factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP	Nucleus Mitochondrial Inner Membrane
	Molecular Function	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding U1 SnRNP Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of MRNA Polyadenylation	Mitochondrial Respiratory Chain Complex I Assembly
Pathways		mRNA Splicing - Major Pathway	Complex I biogenesis
Drugs		Malonic acid
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		53 interacting genes: CDKN2A CHTOP CIRBP DAPK1 DAZAP1 DDIT4L DDX39B EEF1AKNMT ENOX2 FBXO7 FUBP1 GABPB1 GIGYF1 HNRNPK IL7R LENG8 LHX4 LNX1 MBNL2 MRPL15 MTUS2 NDUFAF3 OTX2 PAPOLA PCBP1 PCBP2 PCBP3 PTBP1 PTBP2 QKI RASAL3 RBM11 RBM3 RBM42 RBM4B RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 SDCBP SFPQ SMAD5 SNRPA1 TIAL1 TLE5 TNFAIP8L1 TRIM27 TRIR U2AF2 UBC WBP4 ZCCHC13	17 interacting genes: AGTRAP CABP2 CYSRT1 GEM GOLGA6L9 INCA1 KRT27 KRTAP10-3 LSM1 MBD3L1 NDUFAF4 POU2AF1 RBCK1 REL RNF146 SNRPA UHMK1
Entrez ID		6626	25915
HPRD ID		01658	16809
Ensembl ID		ENSG00000077312	ENSG00000178057
Uniprot IDs		P09012	A4FU71 Q9BU61 Q9Y3Z0
PDB IDs		1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6LAS 6LAU 6LAX 6LAZ 6QX9 6SQN 6SQQ 6SQT 6SQV 6SR7
Enriched GO Terms of Interacting Partners?
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