SNRPA and LENG8

Data Source:
BioGRID (two hybrid, two hybrid)

		SNRPA	LENG8
Description		small nuclear ribonucleoprotein polypeptide A	leukocyte receptor cluster member 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP	Nucleus
	Molecular Function	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding U1 SnRNP Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of MRNA Polyadenylation
Pathways		mRNA Splicing - Major Pathway
Drugs		Malonic acid
Diseases
GWAS		Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		53 interacting genes: CDKN2A CHTOP CIRBP DAPK1 DAZAP1 DDIT4L DDX39B EEF1AKNMT ENOX2 FBXO7 FUBP1 GABPB1 GIGYF1 HNRNPK IL7R LENG8 LHX4 LNX1 MBNL2 MRPL15 MTUS2 NDUFAF3 OTX2 PAPOLA PCBP1 PCBP2 PCBP3 PTBP1 PTBP2 QKI RASAL3 RBM11 RBM3 RBM42 RBM4B RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 SDCBP SFPQ SMAD5 SNRPA1 TIAL1 TLE5 TNFAIP8L1 TRIM27 TRIR U2AF2 UBC WBP4 ZCCHC13	49 interacting genes: ANKHD1 ARID5A ATN1 BAG3 C10orf55 CAMK2A CEP70 CFAP53 COG2 CPSF7 CYSRT1 DMRTB1 DVL3 FAM166B GSE1 HMGXB4 HNRNPM IKBKG INCA1 INTS11 KDM1A LASP1 MAGED1 MAPK1IP1L MIA3 MSX2 MYOZ3 NCBP3 NUTM2F PCID2 PER2 PRDM16 PRMT5 PRMT6 PYGO1 RHOXF2 SMARCB1 SMN1 SMYD1 SNRPA SOCS7 SUV39H1 TFG TLE5 TNIP1 TRAF4 TSG101 VGLL3 ZNF34
Entrez ID		6626	114823
HPRD ID		01658	11226
Ensembl ID		ENSG00000077312	ENSG00000167615
Uniprot IDs		P09012	A0A024R4R9 C9JMY0 Q96PV6
PDB IDs		1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6LAS 6LAU 6LAX 6LAZ 6QX9 6SQN 6SQQ 6SQT 6SQV 6SR7
Enriched GO Terms of Interacting Partners?
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