MTMR9 and MTMR8

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MTMR9	MTMR8
Description		myotubularin related protein 9	myotubularin related protein 8
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Membrane Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Phosphatidylinositol Dephosphorylation Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation	Phosphatidylinositol Biosynthetic Process Negative Regulation Of Autophagy Regulation Of Macroautophagy Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Brain morphology (MOSTest) ( 32665545) Essential hypertension (time to event) ( 32589924) Extraversion ( 27918536) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)
Interacting Genes		26 interacting genes: AATK DEPDC5 EMILIN1 ERBB3 ERBB4 EWSR1 FAM169A GRAMD4 INCA1 KDM1A KIAA1328 KRT27 LNX1 MEI4 MOS MTMR6 MTMR7 MTMR8 NECAB2 NMI PTK7 PTPN3 ROR2 SPG21 VAC14 ZNF655	3 interacting genes: AATK ERBB3 MTMR9
Entrez ID		66036	55613
HPRD ID		09377	06664
Ensembl ID		ENSG00000104643	ENSG00000102043
Uniprot IDs		Q96QG7	Q96EF0
PDB IDs			4Y7I
Enriched GO Terms of Interacting Partners?
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