MTMR8 and MTMR9

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MTMR8	MTMR9
Description		myotubularin related protein 8	myotubularin related protein 9
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol Membrane	Cytoplasm Endoplasmic Reticulum Cytosol Membrane Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity	Phosphatidylinositol-3-phosphatase Activity Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Negative Regulation Of Autophagy Regulation Of Macroautophagy Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Phosphatidylinositol Dephosphorylation Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane	Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Brain morphology (MOSTest) ( 32665545) Essential hypertension (time to event) ( 32589924) Extraversion ( 27918536) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)
Interacting Genes		3 interacting genes: AATK ERBB3 MTMR9	26 interacting genes: AATK DEPDC5 EMILIN1 ERBB3 ERBB4 EWSR1 FAM169A GRAMD4 INCA1 KDM1A KIAA1328 KRT27 LNX1 MEI4 MOS MTMR6 MTMR7 MTMR8 NECAB2 NMI PTK7 PTPN3 ROR2 SPG21 VAC14 ZNF655
Entrez ID		55613	66036
HPRD ID		06664	09377
Ensembl ID		ENSG00000102043	ENSG00000104643
Uniprot IDs		Q96EF0	Q96QG7
PDB IDs		4Y7I
Enriched GO Terms of Interacting Partners?
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