MTMR8 and AATK

Data Source:
BioGRID (two hybrid)

		MTMR8	AATK
Description		myotubularin related protein 8	apoptosis associated tyrosine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol Membrane	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Negative Regulation Of Autophagy Regulation Of Macroautophagy Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		3 interacting genes: AATK ERBB3 MTMR9	43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2
Entrez ID		55613	9625
HPRD ID		06664	05591
Ensembl ID		ENSG00000102043	ENSG00000181409
Uniprot IDs		Q96EF0	H7C175 Q6ZMQ8
PDB IDs		4Y7I
Enriched GO Terms of Interacting Partners?
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