STK33 and SCUBE2

Data Source:
BioGRID (biochemical)

		STK33	SCUBE2
Description		serine/threonine kinase 33	signal peptide, CUB domain and EGF like domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Cell Surface
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Calcium Ion Binding Protein Binding Lipid Binding
	Biological Process	Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Protein Autophosphorylation	Signal Transduction Multicellular Organism Development
Pathways			Release of Hh-Np from the secreting cell
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26426971 19079261 28892062 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Small cell lung carcinoma ( 28604730)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Brain morphology (MOSTest) ( 32665545) Hand grip strength (Mahalanobis distance) ( 32235003)
Interacting Genes		5 interacting genes: APP GLYCTK HPD USP15 USP5	1 interacting genes: SCUBE1
Entrez ID		65975	57758
HPRD ID		09642	18030
Ensembl ID		ENSG00000130413	ENSG00000175356
Uniprot IDs		B3KS39 B4DDH2 F8WAK5 Q9BYT3	B3KS09 Q9NQ36
PDB IDs
Enriched GO Terms of Interacting Partners?
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