SCUBE2 and SCUBE1

Data Source:
HPRD (in vitro)

		SCUBE2	SCUBE1
Description		signal peptide, CUB domain and EGF like domain containing 2	signal peptide, CUB domain and EGF like domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding	Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction Multicellular Organism Development	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Extracellular Matrix Disassembly Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway
Pathways		Release of Hh-Np from the secreting cell	Degradation of the extracellular matrix
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Brain morphology (MOSTest) ( 32665545) Hand grip strength (Mahalanobis distance) ( 32235003)	Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		1 interacting genes: SCUBE1	2 interacting genes: SCUBE2 SCUBE3
Entrez ID		57758	80274
HPRD ID		18030	18029
Ensembl ID		ENSG00000175356	ENSG00000159307
Uniprot IDs		B3KS09 Q9NQ36	A0JP65 Q6ZS56 Q86TI6 Q8IWY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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