SLC13A1 and APLP2

Data Source:
BioGRID (protein complementation assay)

		SLC13A1	APLP2
Description		solute carrier family 13 member 1	amyloid beta precursor like protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome
	Molecular Function	Sodium:sulfate Symporter Activity	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport	Platelet Degranulation G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Sodium-coupled sulphate, di- and tri-carboxylate transporters	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)	Blood protein levels ( 30072576)
Interacting Genes		31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3	23 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B
Entrez ID		6561	334
HPRD ID		08394	00103
Ensembl ID		ENSG00000081800	ENSG00000084234
Uniprot IDs		A4D0X1 Q2NKK0 Q9BZW2	A0A140VJE9 B4E3I5 Q06481
PDB IDs			5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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