Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
APLP2 and APBB1
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, pull down)
HPRD
(in vitro)
APLP2
APBB1
Description
amyloid beta precursor like protein 2
amyloid beta precursor protein binding family B member 1
Image
GO Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum Lumen
Plasma Membrane
Membrane
Integral Component Of Membrane
Platelet Alpha Granule Membrane
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Plasma Membrane
Nuclear Speck
Lamellipodium
Growth Cone
Synapse
Molecular Function
DNA Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Heparin Binding
Identical Protein Binding
Transition Metal Ion Binding
Amyloid-beta Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Ubiquitin Protein Ligase Binding
Histone Binding
Low-density Lipoprotein Particle Receptor Binding
Proline-rich Region Binding
Biological Process
Platelet Degranulation
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Endopeptidase Activity
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle Arrest
Signal Transduction
Axonogenesis
Negative Regulation Of Cell Growth
Positive Regulation Of Apoptotic Process
Histone H4 Acetylation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Secretion
Pathways
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Zinc
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Blood protein levels (
30072576
)
Blood protein levels (
29875488
)
Malaria (
31844061
)
Interacting Genes
23 interacting genes:
AKT1
APBB1
APBB2
APBB3
BRCA1
CDK1
DAB1
DAB2
DEDD
ETS1
HGS
HLA-A
JUN
JUNB
KAT5
MAPK8
PIK3CA
PRKCA
PRNP
RPL26
SLC13A1
VKORC1
ZNF512B
69 interacting genes:
ABI1
ABL1
ANXA1
APLP1
APLP2
APP
ARF6
ATXN1
ATXN1L
CCDC97
CHERP
CLSTN1
CPSF6
CPSF7
CYFIP1
CYFIP2
DDX17
DDX3X
DDX46
DHX15
DHX9
DIAPH1
DIAPH2
EGFR
ELMO1
ENAH
ERBB2
EVL
FASLG
HNRNPH1
HNRNPK
HTATSF1
KAT5
KHDRBS1
KHSRP
LRP1
LRP2
NONO
PABPC1
PQBP1
PRNP
PTBP1
RBM17
RPL4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
TENM1
TFCP2
THRAP3
TSHZ1
TSHZ2
TSHZ3
U2AF2
VASP
WAS
WASF2
WASL
WBP11
WIPF1
WIPF2
YBX1
YLPM1
Entrez ID
334
322
HPRD ID
00103
04087
Ensembl ID
ENSG00000084234
ENSG00000166313
Uniprot IDs
A0A140VJE9
B4E3I5
Q06481
B7Z4M9
O00213
PDB IDs
5JBT
5TPT
2E45
2HO2
2IDH
2OEI
3D8D
3D8E
3D8F
3DXC
3DXD
3DXE
5NQH
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?