ZG16 and KCNIP3

Data Source:
BioGRID (two hybrid)

		ZG16	KCNIP3
Description		zymogen granule protein 16	potassium voltage-gated channel interacting protein 3
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GO Annotations	Cellular Component	Extracellular Space Golgi Lumen Zymogen Granule Membrane Cytoplasmic Vesicle Lumen Collagen-containing Extracellular Matrix Mucus Layer	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Protein-DNA Complex Axon Terminus
	Molecular Function	Protein Binding Carbohydrate Binding Peptidoglycan Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Ion Channel Binding
	Biological Process	Protein Transport Defense Response To Gram-positive Bacterium Suppression Of Symbiont Entry Into Host By Host	Negative Regulation Of Transcription By RNA Polymerase II Intracellular Protein Transport Apoptotic Process Signal Transduction Cardiac Conduction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport
Pathways			Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS			Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		11 interacting genes: ASPH CTNNA3 GLYCTK KCNIP3 PUF60 SGTA SGTB UBE2I UBQLN1 UBQLN2 UBQLN4	26 interacting genes: ASPH C1QTNF2 CALM2 CASP3 CD177 CDSN CLN3 CREB1 CREM CTBP2 GOLGA7 GRK2 GRK6 IGF1R IGLV3-25 IL6ST KHDC4 MAVS PCBD2 PPP3CA PSEN1 PSEN2 SOD3 SRL TARBP2 ZG16
Entrez ID		653808	30818
HPRD ID			05232
Ensembl ID		ENSG00000174992	ENSG00000115041
Uniprot IDs		O60844	A0A024RE22 Q9Y2W7
PDB IDs		3APA 3VY6 3VY7 3VZE 3VZF 3VZG	2E6W
Enriched GO Terms of Interacting Partners?
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