MRPL32 and PRDM14

Data Source:
BioGRID (two hybrid)

		MRPL32	PRDM14
Description		mitochondrial ribosomal protein L32	PR/SET domain 14
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit	Nucleus Nucleoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding
	Biological Process	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Lung cancer in ever smokers ( 28604730) Subcortical volume (MOSTest) ( 32665545)	Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		1 interacting genes: PRDM14	67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835
Entrez ID		64983	63978
HPRD ID		14752	11457
Ensembl ID		ENSG00000106591	ENSG00000147596
Uniprot IDs		A4D1V4 Q9BYC8	Q9GZV8
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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