PRDM14 and MRPL32

Data Source:
BioGRID (two hybrid)

		PRDM14	MRPL32
Description		PR/SET domain 14	mitochondrial ribosomal protein L32
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Transcriptional regulation of pluripotent stem cells	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)	Brain morphology (MOSTest) ( 32665545) Lung cancer in ever smokers ( 28604730) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835	1 interacting genes: PRDM14
Entrez ID		63978	64983
HPRD ID		11457	14752
Ensembl ID		ENSG00000147596	ENSG00000106591
Uniprot IDs		Q9GZV8	A4D1V4 Q9BYC8
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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