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PRDM14 and CARD10
Data Source:
BioGRID
(two hybrid)
PRDM14
CARD10
Description
PR/SET domain 14
caspase recruitment domain family member 10
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
CBM Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Binding
Protein Binding
Methyltransferase Activity
Chromatin DNA Binding
Metal Ion Binding
Protein Binding
Signaling Receptor Complex Adaptor Activity
CARD Domain Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cell Morphogenesis
Cell Fate Specification
Inner Cell Mass Cell Fate Commitment
Regulation Of Transcription By RNA Polymerase II
Germ Cell Development
Embryo Implantation
Fertilization
Regulation Of Gene Expression
Germ-line Stem Cell Population Maintenance
Histone H3-R26 Methylation
Somatic Stem Cell Population Maintenance
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of DNA Methylation
Homeostasis Of Number Of Cells Within A Tissue
Inactivation Of Paternal X Chromosome
Positive Regulation Of Flagellated Sperm Motility
Positive Regulation Of Stem Cell Population Maintenance
Activation Of NF-kappaB-inducing Kinase Activity
Regulation Of Apoptotic Process
Protein-containing Complex Assembly
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Protein Localization To Nucleus
Pathways
Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS
Schizophrenia (
30285260
)
Testicular germ cell tumor (
28604728
28604732
23666240
)
Autoimmune hepatitis type-1 (
24768677
)
Low vWF levels (
26486471
)
Optic disc area (
25631615
31798171
28073927
21307088
)
Optic disc size (
31809533
)
Refractive error (
32231278
)
Vertical cup-disc ratio (
25241763
28073927
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
67 interacting genes:
ABI2
AKAP9
AQP1
ATPAF2
BAG4
BAHD1
BCAR3
BEX2
CARD10
CASP8
CBFA2T2
CDCA7L
CHEK2
CREB5
DGCR6
DMRT3
EED
EIF4E2
ENKD1
ERBB2
EZH2
FAM83A
GAS8
GEM
GLYCTK
GPATCH2L
HEXIM2
HOXB5
HOXC8
HSPB7
ID3
IDH1
KANK2
LNX1
MIA3
MRPL32
MYPOP
PALB2
PATZ1
PAX2
PLEKHF2
PPP1R32
PRKAB2
PRPF31
PSMA1
PTPRJ
RAD51D
RBM10
RCOR3
RUNX1T1
RUSC1
SCNM1
SNRPC
SUZ12
TCAF1
TEAD4
TEKT4
TLE5
TRIM41
TSGA10
TTC32
TXK
USP2
WDR25
ZNF250
ZNF587
ZNF835
105 interacting genes:
ATXN7
BAHD1
BCL10
BCL6B
C4orf45
C8orf48
CARD9
CATSPER1
CBX8
CCDC116
CCDC187
CDC37
CEP95
CHIC2
CNNM3
CWF19L2
CXCL16
CYSRT1
DHX57
DOCK2
DUSP26
FAM47B
FOXD4L3
GADD45GIP1
GAS8
GFAP
GIPC1
GPATCH2L
GSE1
GSTP1
HBZ
HOXB9
IKBKG
IL16
JOSD1
KANK2
KDM1A
KEAP1
KLHL12
KRT75
KRTAP10-8
KRTAP12-3
KRTAP26-1
KRTAP9-2
KRTAP9-3
LENG1
MAGOHB
METTL17
MITD1
MYPOP
NME7
OLIG3
PIBF1
PKP1
PNKP
PRDM14
PRPF18
PRPF3
PRR35
PTCD1
PTGDS
RIN1
SCNM1
SEMA3B
SPATA18
TBC1D22B
TBC1D26
TFAP2D
TMEM43
TRIM27
TRIM41
USP54
UTP14C
ZBTB26
ZFP1
ZNF10
ZNF12
ZNF165
ZNF180
ZNF202
ZNF223
ZNF239
ZNF250
ZNF285
ZNF286A
ZNF32
ZNF329
ZNF366
ZNF414
ZNF415
ZNF439
ZNF440
ZNF524
ZNF552
ZNF559
ZNF564
ZNF575
ZNF581
ZNF587
ZNF613
ZNF670
ZNF775
ZNF80
ZNF837
ZSCAN25
Entrez ID
63978
29775
HPRD ID
11457
06233
Ensembl ID
ENSG00000147596
ENSG00000100065
Uniprot IDs
Q9GZV8
Q9BWT7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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