CENPH and ZNF493

Data Source:
BioGRID (two hybrid)

		CENPH	ZNF493
Description		centromere protein H	zinc finger protein 493
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Nucleus
	Molecular Function	Protein Binding Kinetochore Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Generic Transcription Pathway
Drugs
Diseases
GWAS			Height ( 28552196) Nickel levels ( 26025379)
Interacting Genes		19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12	2 interacting genes: CENPH MESD
Entrez ID		64946	284443
HPRD ID		12029	15804
Ensembl ID		ENSG00000153044	ENSG00000196268
Uniprot IDs		A0A0S2Z5T0 Q9H3R5	Q6ZR52
PDB IDs
Enriched GO Terms of Interacting Partners?
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