CENPH and RASSF4

		CENPH	RASSF4
Description		centromere protein H	Ras association domain family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	Protein Binding Kinetochore Binding	Protein Binding
	Biological Process	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Cell Cycle Signal Transduction
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis ( 31749835)
Interacting Genes		19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12	6 interacting genes: CENPH HGS HMGB1 IFT20 MAGEA6 STK3
Entrez ID		64946	83937
HPRD ID		12029	15219
Ensembl ID		ENSG00000153044	ENSG00000107551
Uniprot IDs		A0A0S2Z5T0 Q9H3R5	Q9H2L5
PDB IDs
Enriched GO Terms of Interacting Partners?
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