ZNF493 and CENPH

Data Source:
BioGRID (two hybrid)

		ZNF493	CENPH
Description		zinc finger protein 493	centromere protein H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Metal Ion Binding	Protein Binding Kinetochore Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization
Pathways		Generic Transcription Pathway	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Height ( 28552196) Nickel levels ( 26025379)
Interacting Genes		2 interacting genes: CENPH MESD	19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12
Entrez ID		284443	64946
HPRD ID		15804	12029
Ensembl ID		ENSG00000196268	ENSG00000153044
Uniprot IDs		Q6ZR52	A0A0S2Z5T0 Q9H3R5
PDB IDs
Enriched GO Terms of Interacting Partners?
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