RNF25 and KCTD21

		RNF25	KCTD21
Description		ring finger protein 25	potassium channel tetramerization domain containing 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding NF-kappaB Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding Histone Deacetylase Binding Cullin Family Protein Binding
	Biological Process	Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Growth Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072)	Tourette syndrome ( 30818990)
Interacting Genes		11 interacting genes: KCTD21 MEOX2 RELA TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2E2 UBE2E3 UBE2L6 UBE2U	9 interacting genes: C22orf15 CRLF3 LONRF1 NMRK1 NTAQ1 PPL RNF25 UFM1 ZMYND19
Entrez ID		64320	283219
HPRD ID		09737	18763
Ensembl ID		ENSG00000163481	ENSG00000188997
Uniprot IDs		Q96BH1	Q4G0X4
PDB IDs		2DAY 2DMF 5D1K 5D1L 5D1M
Enriched GO Terms of Interacting Partners?
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