KCTD21 and RNF25

		KCTD21	RNF25
Description		potassium channel tetramerization domain containing 21	ring finger protein 25
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol
	Molecular Function	Protein Binding Identical Protein Binding Histone Deacetylase Binding Cullin Family Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding NF-kappaB Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Growth Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization	Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Tourette syndrome ( 30818990)	Male-pattern baldness ( 28196072)
Interacting Genes		9 interacting genes: C22orf15 CRLF3 LONRF1 NMRK1 NTAQ1 PPL RNF25 UFM1 ZMYND19	11 interacting genes: KCTD21 MEOX2 RELA TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2E2 UBE2E3 UBE2L6 UBE2U
Entrez ID		283219	64320
HPRD ID		18763	09737
Ensembl ID		ENSG00000188997	ENSG00000163481
Uniprot IDs		Q4G0X4	Q96BH1
PDB IDs			2DAY 2DMF 5D1K 5D1L 5D1M
Enriched GO Terms of Interacting Partners?
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