SRSF7 and SREK1

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SRSF7	SREK1
Description		serine and arginine rich splicing factor 7	splicing regulatory glutamic acid and lysine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	MRNA Processing RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		18 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 LUC7L LUC7L2 NEDD4 NXF1 PCBP2 PRPF38A RNPS1 SDCBP SREK1 SRPK1 SRPK2	60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		6432	140890
HPRD ID		08991	18043
Ensembl ID		ENSG00000115875	ENSG00000153914
Uniprot IDs		Q16629	Q8WXA9
PDB IDs		2HVZ
Enriched GO Terms of Interacting Partners?
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