SREK1 and SRSF5

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SREK1	SRSF5
Description		splicing regulatory glutamic acid and lysine rich protein 1	serine and arginine rich splicing factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleoplasm Nucleolus Cytosol Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding
	Biological Process	MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Cellular Response To Insulin Stimulus Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Liver Regeneration
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2	20 interacting genes: CALM1 CCR2 CD101 CLK1 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TIAM1 TNK2 ZRSR2
Entrez ID		140890	6430
HPRD ID		18043	02948
Ensembl ID		ENSG00000153914	ENSG00000100650
Uniprot IDs		Q8WXA9	A0A024R6D8 Q13243 Q86U32
PDB IDs
Enriched GO Terms of Interacting Partners?
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