MS4A6A and GPRC5D

Data Source:
BioGRID (two hybrid)

		MS4A6A	GPRC5D
Description		membrane spanning 4-domains A6A	G protein-coupled receptor class C group 5 member D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Trans-Golgi Network Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process		G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 21460840) Alzheimer's disease (late onset) ( 30617256 24162737 28714976) Alzheimer's disease in APOE e4- carriers ( 25778476) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) C-reactive protein levels ( 30388399) Cerebrospinal fluid sTREM-2 levels ( 31708768) Factor VII activity ( 30642921) Factor VII activity or levels ( 30642921) Family history of Alzheimer's disease ( 30617256) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549 28869591) Lymphocyte percentage of white cells ( 32888494) Methadone dose in opioid dependence ( 28115739) Neutrophil count ( 32888494)
Interacting Genes		1 interacting genes: GPRC5D	30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1
Entrez ID		64231	55507
HPRD ID		09414	07604
Ensembl ID		ENSG00000110077	ENSG00000111291
Uniprot IDs		A0A024R516 A0A024R554 B4DUN6 E9PSA9 Q9H2W1	Q9NZD1
PDB IDs
Enriched GO Terms of Interacting Partners?
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