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GPRC5D and CCL4
Data Source:
BioGRID
(two hybrid)
GPRC5D
CCL4
Description
G protein-coupled receptor class C group 5 member D
C-C motif chemokine ligand 4
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Receptor Complex
Extracellular Exosome
Extracellular Region
Extracellular Space
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
Protein Kinase Activator Activity
Cytokine Activity
Protein Binding
Chemokine Activity
CCR1 Chemokine Receptor Binding
CCR5 Chemokine Receptor Binding
Identical Protein Binding
CCR Chemokine Receptor Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Activation Of Protein Kinase Activity
Monocyte Chemotaxis
Inflammatory Response
Immune Response
Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Response To Toxic Substance
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
Positive Regulation Of GTPase Activity
Negative Regulation By Host Of Viral Transcription
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Calcium-mediated Signaling
Positive Regulation Of Calcium Ion Transport
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Drugs
Diseases
GWAS
Blood protein levels in cardiovascular risk (
28369058
)
Body mass index (
26426971
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
30 interacting genes:
APOL3
BTN2A2
C14orf180
C1GALT1
CCL4
EMP1
ERMP1
FXYD3
FXYD6-FXYD2
GYPA
IFITM3
IGFBP5
LHFPL5
LRRC25
MS4A6A
OSMR
PMP22
PRRT2
PVR
SLC30A2
SLC66A1
SYNDIG1
TMEM120B
TMEM19
TMEM208
TMEM79
TRARG1
TWSG1
UNC93B1
YIPF1
26 interacting genes:
ACKR2
ARL13B
CCL3
CCR1
CCR3
CCR5
CCR8
CNR2
CXCL8
GJA8
GPR152
GPRC5D
MARCHF2
MRM1
SLC10A6
SLC18A1
SLC30A2
SLC30A8
SLC7A1
TAS2R5
TIMMDC1
TMEM14B
TMEM179B
TMEM31
TMEM86B
UNC93A
Entrez ID
55507
6351
HPRD ID
07604
01657
Ensembl ID
ENSG00000111291
ENSG00000275302
Uniprot IDs
Q9NZD1
P13236
PDB IDs
1HUM
1HUN
1JE4
2FFK
2FIN
2X6L
3TN2
4RAL
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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