GPRC5D and GYPA

Data Source:
BioGRID (two hybrid)

		GPRC5D	GYPA
Description		G protein-coupled receptor class C group 5 member D	glycophorin A (MNS blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Virus Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity	Viral Entry Into Host Cell Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Lung function (low FEV1 vs high FEV1) ( 26423011) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)
Interacting Genes		30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	24 interacting genes: ANKRD29 CLDN5 CREB3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31
Entrez ID		55507	2993
HPRD ID		07604	07508
Ensembl ID		ENSG00000111291	ENSG00000170180
Uniprot IDs		Q9NZD1	A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419
PDB IDs			1AFO 1MSR 2KPE 2KPF 5EH4 5EH6
Enriched GO Terms of Interacting Partners?
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