STRA6 and GLRX3

Data Source:
BioGRID (two hybrid)

		STRA6	GLRX3
Description		signaling receptor and transporter of retinol STRA6	glutaredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Protein-containing Complex	Nucleus Cytosol Cell Cortex Z Disc Dendrite
	Molecular Function	Retinal Binding Retinol Binding Retinol Transmembrane Transporter Activity Signaling Receptor Activity	RNA Binding Protein Kinase C Binding Protein Binding Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Retinoid Metabolic Process Blood Vessel Development Kidney Development Pulmonary Valve Morphogenesis Ventricular Septum Development Heart Development Learning Feeding Behavior Lung Development Adrenal Gland Development Female Genitalia Development Retinol Transport Vocal Learning Camera-type Eye Development Ear Development Nose Morphogenesis Lung Alveolus Development Positive Regulation Of Behavior Digestive Tract Morphogenesis Embryonic Digestive Tract Development Developmental Growth Smooth Muscle Tissue Development Artery Morphogenesis Cognition Neuromuscular Process Head Development Head Morphogenesis Face Morphogenesis Lung Vasculature Development Diaphragm Development Embryonic Camera-type Eye Formation Eyelid Development In Camera-type Eye Uterus Morphogenesis Alveolar Primary Septum Development Pulmonary Artery Morphogenesis Paramesonephric Duct Development Vitamin A Import Ductus Arteriosus Closure	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy [2Fe-2S] Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)	Iron uptake and transport
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Inhibitory control ( 29251981) Optic disc size ( 31809533)	Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		4 interacting genes: GLRX3 KRTAP10-6 KRTAP6-3 NDUFB7	99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA1 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CERCAM CGGBP1 CIAPIN1 COL8A1 EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774
Entrez ID		64220	10539
HPRD ID		18122	10153
Ensembl ID		ENSG00000137868	ENSG00000108010
Uniprot IDs		B3KPB8 Q9BX79	A0A140VJK1 O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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