BLMH and TNPO3

Data Source:
BioGRID (two hybrid)

		BLMH	TNPO3
Description		bleomycin hydrolase	transportin 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Identical Protein Binding	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Polyubiquitination Proteolysis Response To Toxic Substance Response To Drug Homocysteine Catabolic Process	Protein Import Into Nucleus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		20 interacting genes: AP1M2 APP CDC42 CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NUDT12 NXF1 PDPK1 PGLS RNF32 RPL11 RPL29 TNPO2 TNPO3 TRIM47 TRIO UBE2I	19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B
Entrez ID		642	23534
HPRD ID		03870	18209
Ensembl ID		ENSG00000108578	ENSG00000064419
Uniprot IDs		Q13867	A0A024R794 B3KMX1 Q9Y5L0
PDB IDs		1CB5 2CB5	4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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