TNPO3 and BLMH

Data Source:
BioGRID (two hybrid)

		TNPO3	BLMH
Description		transportin 3	bleomycin hydrolase
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GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Identical Protein Binding
	Biological Process	Protein Import Into Nucleus	Protein Polyubiquitination Proteolysis Response To Toxic Substance Response To Drug Homocysteine Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B	20 interacting genes: AP1M2 APP CDC42 CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NUDT12 NXF1 PDPK1 PGLS RNF32 RPL11 RPL29 TNPO2 TNPO3 TRIM47 TRIO UBE2I
Entrez ID		23534	642
HPRD ID		18209	03870
Ensembl ID		ENSG00000064419	ENSG00000108578
Uniprot IDs		A0A024R794 B3KMX1 Q9Y5L0	Q13867
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9	1CB5 2CB5
Enriched GO Terms of Interacting Partners?
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