TNPO3 and PPP1R1C

Data Source:
BioGRID (two hybrid)

		TNPO3	PPP1R1C
Description		transportin 3	protein phosphatase 1 regulatory inhibitor subunit 1C
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle	Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Protein Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Protein Import Into Nucleus	Cell Cycle Negative Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Cell Division
Pathways
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)	Hip circumference adjusted for BMI ( 28552196) Systolic blood pressure ( 30578418)
Interacting Genes		19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B	1 interacting genes: TNPO3
Entrez ID		23534	151242
HPRD ID		18209	15169
Ensembl ID		ENSG00000064419	ENSG00000150722
Uniprot IDs		A0A024R794 B3KMX1 Q9Y5L0	Q8WVI7
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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