SET and MTERF1

Data Source:
BioGRID (pull down)

		SET	MTERF1
Description		SET nuclear proto-oncogene	mitochondrial transcription termination factor 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding	Nucleic Acid Binding Double-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	DNA Replication Nucleosome Assembly Nucleosome Disassembly Viral Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Histone Acetylation Regulation Of MRNA Stability Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Termination Of Mitochondrial Transcription Mitochondrion Organization DNA Geometric Change
Pathways		Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA	Mitochondrial transcription termination Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)	Blond vs. brown/black hair color ( 30531825) Hemoglobin levels ( 32327693)
Interacting Genes		68 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 REPIN1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UCHL5 XRCC6 ZNF17 ZNF438 ZNF85	6 interacting genes: DCTN1 DNAJC21 EXOC6B SET SYTL2 TMEM128
Entrez ID		6418	7978
HPRD ID		09023	08373
Ensembl ID		ENSG00000119335	ENSG00000127989
Uniprot IDs		A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3	B4DPR9 Q99551
PDB IDs		2E50	3MVA 3MVB 3N6S 3N7Q 5CKY 5CO0 5CRJ 5CRK
Enriched GO Terms of Interacting Partners?
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