KIF9 and TRIM37

Data Source:
BioGRID (two hybrid)

		KIF9	TRIM37
Description		kinesin family member 9	tripartite motif containing 37
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GO Annotations	Cellular Component	Podosome Cytoplasm Kinesin Complex Microtubule Vesicle	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Identical Protein Binding	Chromatin Binding Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Microtubule-based Movement Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Huntington's disease progression ( 28642124) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Cognitive function ( 25644384) General cognitive ability ( 29844566) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239)
Interacting Genes		63 interacting genes: ACBD4 ALAS1 AMOTL2 ATP5IF1 BLZF1 CARD9 CCDC125 CYTIP DISC1 EFHC2 EMD FXR1 GOLGA6A HMBOX1 HOOK2 HSF2BP IHO1 IKZF1 IKZF3 INKA1 IQCB1 JAKMIP2 KANK2 KCTD9 KRT75 KRTAP10-3 KRTAP10-6 KRTAP10-9 LZTS1 LZTS2 MAD1L1 MID1 MID2 MIPOL1 NAB2 OIP5 OOEP PIBF1 PNMA5 PPP1R13B PRICKLE1 PRMT6 RBM48 RBM5 ROPN1 SHISA6 SLAIN1 SSX2IP STEEP1 TFIP11 TRIM27 TRIM37 TRIM54 VIM VPS52 ZBTB8A ZC2HC1C ZCCHC7 ZNF417 ZNF436 ZNF566 ZNF572 ZRANB1	73 interacting genes: ANKRD11 APEX2 APTX AQP1 ARNT2 AXIN1 BYSL CCDC33 CDC20B CDC7 CDK5RAP2 CDKL3 COPB1 CWF19L2 DDX6 DLGAP5 DTNB DZIP1L ELOA ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 SYTL4 TCEANC TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZBTB24 ZMAT2 ZNF329 ZNF417 ZNF587 ZNF655
Entrez ID		64147	4591
HPRD ID		07444	05463
Ensembl ID		ENSG00000088727	ENSG00000108395
Uniprot IDs		A8K932 Q9HAQ2	O94972
PDB IDs		3NWN	3LRQ
Enriched GO Terms of Interacting Partners?
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