TRIM37 and ZBTB24

Data Source:
BioGRID (two hybrid)

		TRIM37	ZBTB24
Description		tripartite motif containing 37	zinc finger and BTB domain containing 24
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly	Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 25644384) General cognitive ability ( 29844566) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239)	Depression in smokers ( 30219690) Height ( 20881960 18391951)
Interacting Genes		73 interacting genes: ANKRD11 APEX2 APTX AQP1 ARNT2 AXIN1 BYSL CCDC33 CDC20B CDC7 CDK5RAP2 CDKL3 COPB1 CWF19L2 DDX6 DLGAP5 DTNB DZIP1L ELOA ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 SYTL4 TCEANC TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZBTB24 ZMAT2 ZNF329 ZNF417 ZNF587 ZNF655	70 interacting genes: BACH2 BAX BCL11A BLZF1 C4orf45 CALM1 CCDC136 CCNDBP1 CDA CEP70 CEP76 DDHD1 DNM1L DVL3 FCHO1 GMCL1 GOLGA6L9 HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP5-9 LDOC1 LHX8 LNX1 LRRC18 MCIDAS MDFI MID2 PDE4DIP PHC2 PICK1 POGZ POU6F2 PRMT7 RALY RBM10 RIN3 SSX2IP SUV39H1 TLE5 TMEM121 TRAF2 TRIM37 TRIM41 TSC22D4 TSGA10 TSPYL2 ZBTB43 ZBTB8A ZBTB9 ZMYM6 ZNF526 ZNF639 ZNF71 ZNF79 ZNF792 ZNF837 ZRANB1
Entrez ID		4591	9841
HPRD ID		05463	18315
Ensembl ID		ENSG00000108395	ENSG00000112365
Uniprot IDs		O94972	O43167
PDB IDs		3LRQ
Enriched GO Terms of Interacting Partners?
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